Growth Hormone Human Epidermal Growth Factor HEX Examorelin Acetate
Hexarelin (Hexarelin Acetate) is a synthetic hexapeptide in the
growth factor family which stimulates the release of growth hormone
(GH) and does not interfere with the body's ability to produce its
own GH. Structurally, Hexarelin (Hexarelin Acetate) is similar in
structure to GHRP-6 but without the appetite increase because of
its inability to drastically increase Ghrelin levels which is
responsible for the increased appetite and quicker gastric
emptying. Hexarelin is a synthetic growth hormone secretagogue made
from six amino acids.
It contains powerful growth hormone releasing properties in the
human body. Hexarelin in studies over a certain period has shown
that it reduces visceral fat. Hexarelin (Hexarelin Acetate) like
other Growth hormone releasing peptides is most effective
synergistically when administered with GHRH such as Sermorelin or
Modified GRF 1-29. The increase of circulating GH through Hexarelin
use causes levels of Insulin-Like Growth Factor (IGF-1) to rise in
the liver. IGF-1 is the prime cause of muscle growth in response to
GH stimulation. Users of IGF-1 typically experience increased
strength and muscle mass, as well as a very pronounced fat loss.
Hexarelin Acetate Structure
Molecular formula: C47H58N12O6
Molar Mass: 887.04022
CAS number: 140703-51-1
PubChem: CID 5464109
Synonyms: Hexarelin Acetate, HEX, Examorelin
The functionality of Hexarelin
Hexarelin (Hexarelin Acetate) is chemically designed as
Hexarelin (Hexarelin Acetate) is a potent GHRP-6 analog, whose
structure (His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2) creates a
greater stability than GHRP-6 due to a substituted (2 Me)Trp. Hexarelin has a half-life of about 70 min, longer than that of GHRP-6.
Replacement of the naturally occurring L-amino acids for the
D-configuration results in these longer half-lives.
Growth Hormone Secretion
Hexarelin has shown that it is highly stimulated at 30 minutes
after being induced by rapid and sustained GH secretion. The
pituitary gland produces GH in the brain, in children this hormone
helps them to grow and in adults it helps to maintain muscle and
burn fat. In one sixteen-week study, it has been shown that GH
levels return to normal after stopping use after four weeks.
Hexarelin, also known as Examorelin, is a Growth Hormone (GH), specifically a Growth Hormone Secretagogue Receptor (GHSR)
of the hexapeptide class. Hexarelin is in many ways similar to GHRP-6; however, it has been shown to be much stronger producing a larger
increase in naturally produced GH. Some data suggest it may be the
strongest synthetic Growth Hormone Releasing Hormone (GHRH) on the
Hexarelin Functions and Traits
Hexarelin is comprised of a chain of amino acids that when
administered stimulates the pituitary in a pulsating fashion
causing it to release more GH into the body. Unfortunately, at this
time it is not fully understood how Hexarelin causes such a strong
increase in GH compared to say GHRP-6; data merely shows that the
increase is significantly more.
The use of Hexarelin has also been shown to increase prolactin and
cortisol levels in the body, far more so than other GH products.
Prolactin increases should not be as strong as they may be with
certain anabolic steroids, but they may be significant in some cases. Hexarelin will not
increase Ghrelin levels in the body like GHRP-6 despite being very
similar on a structural basis.
Data has also shown Hexarelin to be one of the faster acting GH
products on the market but also one of the few that stops working
after a set amount of time. GH levels should increase quickly and
in a beneficial manner in as little as four weeks. However, use
past the sixteen week mark has been shown to produce little to no
results. Use of any worth will normally fall in the 8-12 week range
with 4-6 weeks of no use (minimum) between Hexarelin cycles. The
peptide will not render pituitary function (GH production) post use
as will anabolic steroids in regards to the testicles, but it does appear to have a short
lived actionable period of use.
Effects of Hexarelin
As with all GH products, Hexarelin carries with it numerous
benefits. Because it is one of the most power GHRH hormones on the
market, it may be the most beneficial to the performance athlete. Human Growth Hormone (HGH) will always be the most effective of all, but when it comes to
GHRH items, fragments and the like, Hexarelin is perhaps the top
The off-season athlete should find increases in mass and strength,
increased recovery and an ability to maintain lower levels of body
fat all a reality with this compound. As with any GH product,
results will be dependent on diet and training routines, but also
strongly dependent on the other items being used. The user will
find his anabolic steroid cycle or other performance based items to be far more effective when
using a GH product. He will not find a lot of benefit in terms of
anabolism when used alone.
For the cutting athlete, much of what’s said for the off-season
athlete can be said again, but in this case, it’s the fat loss, the
enhanced metabolism that’s most beneficial. Recovery will also play
a large role in terms of benefits being that recovery often suffers
during a hard diet. Important note – although significant anabolism
will not be present when used alone in an off-season, if used alone
when cutting, increased rates in fat burning will certainly exist.
Perhaps the most beneficial effects of Hexarelin surround its
healing properties. Data has shown this to be one of the most
beneficial GH products in this regard. We cannot call it a suitable
long-term option for the purpose of anti-aging due to the
short-lived use that seems to exist, but it’s recovery type
benefits are still hard to ignore. Such benefits can include:
- Joint healing (not masking or false pain relief, but actual
- Strengthening of the Neural system
- Muscle fiber repair (ideal for injuries)
- Direct increase of bone density
- Heart protection (some data has shown it may heal heart tissue,
including the healing of scar tissue to the relieving of pressure
at the left ventricle)
Side Effects of Hexarelin
The side effects of Hexarelin, there are more possible negative
effects with this GH hormone than most but they should still be
minimal in most cases. Most of the common yet infrequent side
effects of GH can exist, but the side effects of Hexarelin do
outnumber some of the other compounds GH related compounds:
- Estrogenic: The side effects of Hexarelin do not include those of a direct
estrogenic nature. Water retention is possible but not due to
elevated levels of estradiol and can usually be corrected through
diet, exercise or dosing adjustments.Hexarelin does not aromatize,
but it can promote gynecomastia due to its ability to increase prolactin. This will not be a concern for most; it will most commonly be a
concern for those who already possess active gynecomastia. However,
in sensitive individuals or those who are already using items that
increase prolactin, it could prove to be problematic.
- Androgenic: The side effects of Hexarelin do not include any of an androgenic
nature. Acne and hair loss are not possible with this peptide.
Virilization symptoms cannot occur in women due to this peptide.
- Cardiovascular: Cholesterol and blood pressure should not be negatively affected
by the use of Hexarelin. Data has shown that the peptide may in
fact improve heart health.
- Hepatotoxicity: Hexarelin is not liver toxic.
- Testosterone Suppression: Hexarelin will not suppress natural testosterone production.
- Cortisol: The side effects of Hexarelin may include elevated levels of
cortisol. How significant it will be appears to be very
individualistic and may also be affected by other hormones you are
taking. Individuals with elevated levels of cortisol may suffer
from insomnia or restless sleep, they may experience fat gain
despite proper diet and exercise, and they may find they have a
weaker immune system. Depression, a decreased libido and increased
anxiety may also be signs of elevated cortisol levels.
Hexarelin is administered via a subcutaneous injection. It will
come in dry powder form and is mixed with bacteriostatic water.
200mcg per day appears to be the best dose for most in terms of
benefits, although some may go as high as 400mcg per day. Users
that use 400mcg per day do, however, run the risk of pituitary
flair up. Most data shows benefits of 200mcg per day are not
exceeded with higher doses of Hexarelin.
Due to the inactivity that will occur in time, 16 weeks of use max
is the general recommendation with a minimum of 4 weeks of no use
before starting again. Most users will find 8-12 weeks to be the
most effective and beneficial time frame.
Buy Hexarelin Online
You can buy Hexarelin online from an online research chemical
supply company. This will be the only place most will find it, and
you will find the majority of related online vendors do not sell
it. It can be one of the more expensive peptides available online
and while not carried by all is carried by enough to find it. If
you decide to buy Hexarelin online it is imperative that you first
understand the laws of your country as they can vary from one to
the next. In the U.S. such a purchase is legal but only for
research purposes. You cannot legally buy Hexarelin online for
individual personal use.
Hexarelin does appear to have a lot of potential in the world of GH
hormones. It may also be one of the more exciting ones being that
it’s far less expensive than HGH and far more effective in terms of
immediate benefits compared to most related items. However, because
it is still a relatively new compound and because a lot of data
still has holes, it’s very difficult to give a true opinion on this
product at this time.